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Description

By interacting with actin monomers and influencing actin filament formation, TB-500 can alter how cells move, attach, and reorganize within damaged or remodeling tissues

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doi: 10.1016/j.ccc.2022.07.007 [PubMed] 36333039 Coppler PJ, Elmer J

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Das ist vor allem bei empfindlicheren Wirkstoffen sinnvoll

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Cellular signaling and biological functions of R-spondins

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The Phase 2 NEJM trial showed 24.2% average body weight reduction at 48 weeks in the 12mg group

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